The lipogenesis pathway as a cancer target

J Med Chem. 2011 Aug 25;54(16):5615-38. doi: 10.1021/jm2005805. Epub 2011 Aug 3.

Author

Hanley N Abramson¹

Affiliation

¹ Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, Michigan 48201, USA. ac2531@wayne.edu

PMID: 21726077
DOI: 10.1021/jm2005805

No abstract available

MeSH terms

ATP Citrate (pro-S)-Lyase / antagonists & inhibitors
ATP Citrate (pro-S)-Lyase / metabolism
Acetyl-CoA Carboxylase / antagonists & inhibitors
Acetyl-CoA Carboxylase / metabolism
Animals
Antineoplastic Agents / chemistry
Antineoplastic Agents / therapeutic use*
Biosynthetic Pathways / drug effects*
Fatty Acid Synthases / antagonists & inhibitors
Fatty Acid Synthases / metabolism
Fatty Acids / biosynthesis
Fatty Acids / chemistry
Humans
Lipogenesis / drug effects*
Models, Chemical
Molecular Structure
Neoplasms / drug therapy*
Neoplasms / metabolism

Substances

Antineoplastic Agents
Fatty Acids
Fatty Acid Synthases
ATP Citrate (pro-S)-Lyase
Acetyl-CoA Carboxylase